Chapters Transcript Video scc_ipsen0220_somatuline-depot-formulation-video so masculine Depot Landry A tied 120 mg. Understanding its formulation and administration. So Masculine Depot Landry A tide is the first and on Lisa Mata Staten Analog that is, FDA approved to treat both adult patients with UN respectable, well or moderately differentiated, locally advanced or metastatic gastro intro. Pancreatic neuro endocrine tumors or get nuts to improve progression free survival and adults with carcinoid syndrome. When used, it reduces the frequency of short acting Samata Staten Analog rescue therapy So Masculine Depot is contra indicated in patients with hypersensitivity toe landry. A tide allergic reactions, including angio, oedema and an awful axis, have been reported following administration of Landry A. Tied It is important to understand the warnings and precautions for some Atul in Depot include cola thigh, Asus and gall bladder sludge, hypoglycemia or hyperglycemia and cardiovascular abnormalities. Please listen to the additional safety information later in this video, so match Elin Depot, especially formulated to streamline preparation and administration. So match Ling depot comes in a ready to use pre filled syringe. There is no reconstitution required, so match. Elin Depot is intended for administration by a health care provider. E proprietary nanotechnology of some. Atul in Depot consists of two ingredients. Densely packed, dissolved landry, a tight molecules and water. There are no polymers or long acting additives, a za result so naturally, Depot has a low injection volume. 0.5 mL. Theo Unique formulation enables a once monthly delivery of 120 mg b a deep subcutaneous injection. Do not administer intra muscularly if a patient is accidentally administered so masculine depot, intra muscularly thin. Do not repeat the dose until the next regularly scheduled dozing interval. So naturally, depot is delivered into the soft, fatty layer of tissue just underneath the skin. After injection, a depot or drug reservoir is formed for fast acting and sustained release drug delivery, so match Elin Depot passively diffuses into surrounding tissue and is then absorbed into the bloodstream. Within a short time, the serum concentration level reaches its peak. Maximum drug levels are achieved by day. One. Depot continues to deliver steady and sustained medication until the next monthly dose. Sustained release is possible, with some actual in depot because it is slowly absorbed by the surrounding tissue and has a long terminal, half life land Rio type thing. Active ingredient of some. Actually, depot is an octopus tied analog of natural Samata Staten. Its mechanism of action is believed to be similar to that of natural Samata Staten So mad. A statin is a naturally occurring inhibitory peptide that is expressed in neuro endocrine cells. Land Rio tied binds toe. All known Samata Staten receptors S S T R s one through five. It has high affinity for S S t R two and five and reduced affinity for S S T R. 13 and four. A unique formulation of some Actually, Depot streamlines preparation and administration. Some Atul in Depot provides once monthly dozing via deep subcutaneous injection from a pre filled and ready to use syringe toe. Learn mawr. Go to Samantha Lean Depot HCP dot com Important safety information. So match Elin Depot is contra indicated and patients with hypersensitivity tow land Rio Tied allergic reactions including angio oedema and animal axis, have been reported following administration of land Rio tied so match Elin Depot may reduce gall bladder motility and lead to gall stone formation. Periodic monitoring may be needed if complications of cola Mathias is are suspected. Discontinue. So match Elin Depot and treat appropriately. Patients treated with some Atul in Depo may experience hypoglycemia or hyperglycemia. Blood glucose levels should be monitored when some Atul in Depot treatment is initiated, or when the doses altered. An anti diabetic treatment should be adjusted accordingly. So match Lynn Depot may decrease heart rate in patients without underlying cardiac disease. So match Elin Depot may lead to a decrease in heart rate without necessarily reaching the threshold of bradycardia in patients suffering from cardiac disorders prior to treatment, Sinus bradycardia may occur. Care should be taken when initiating treatment in patients with bradycardia. Adverse reactions and greater than 10% of patients who received some actually in depot in the Gap Net trial were abdominal pain, musculoskeletal pain, vomiting, headache, injection, site reaction, hyperglycemia, hypertension and cola thigh Asus. Adverse reactions occurring in the carcinoid syndrome tri ALS were generally similar to those in the Gap. Net trial adverse reactions and greater than 5% of patients who received some actually in depot and at least 5% greater than placebo were headache, dizziness and muscle spasm. So naturally in depo may decrease the absorption of cyclosporine. Dosage adjustment may be needed. Increase the absorption of Roma Christine and required dosage adjustment for bradycardia inducing drugs. For example, beta blockers advised women not to breastfeed during treatment and for six months after the last dose to report suspected adverse reactions. Contact Gibson Biopharmaceuticals Inc at 1855 or 635127 or FDA at 1 800. FDA 1088 or www dot f d a dot gov forward slash med Watch. Please see the full prescribing information and patient information for some Atul in Depot at w w w dot some match ling depot HCP dot com Published Created by
